Creutzfeldt–Jakob Disease and the Risk from Blood or Blood Products

The factors that affect blood and blood products usage in coronary artery graft surgery

Background: Coronary artery bypass surgery is one of the surgeries in which high blood transfusions are needed. About 20% of all surgical operations require a blood transfusion. Packed cell administration increases perioperative morbidity and mortality. In the United States, from every 1000 people, one has undergone a coronary artery bypass graft surgery, and it is estimated that around 800,000...

Risk Analysis of New Variant Creutzfeldt-jakob Disease Transmission by Blood and Blood Products

Variant Creutzfeldt-Jakob disease: risk of transmission by blood and blood products.

Variant Creutzfeldt-Jakob disease (CJD) is a novel acquired human prion disease apparently resulting from exposure to the bovine spongiform encephalopathy (BSE) agent. Variant CJD differs from other human prion diseases in that the disease-associated form of the prion protein and infectivity are readily detectable in lymphoid tissues throughout the body. Lymphoid tissues and lymphocytes are imp...

Investigation on artificial blood or substitute blood replace the natural blood

Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of different cells The reduction of unwanted side effects, especially diseases that emerge through blood such as HIV and hepatitis, has a significant role for modern medicine of transfusion and transplantation. The issues and costs of human blood collection and storage, direct this procedure towards t...

Immunological reactions to blood and blood products.

All blood cells possess inherited antigens; their pattern is specific for any individual or groups of individuals, and remains constant throughout life. Although the majority of the antigens were first recognized in association with blood cells, it is now evident that many of them are also found in other tissues and in body fluids, and specific antigens have been demonstrated in plasma. Antibod...